Your Body's Most Advanced Regenerative Biology — PRF at Derma Radiance & Wellness
There is a new standard in natural regenerative aesthetics — and it starts with your own blood.
PRF, or Platelet-Rich Fibrin, is the next generation of regenerative injectable therapy. More concentrated, more biologically active, and longer-lasting than traditional PRP, PRF harnesses a richer spectrum of your body's own growth factors, fibrin, and white blood cells to restore skin quality, address under-eye hollowing, and revitalize thinning hair — with no synthetic substances, no foreign fillers, and no additives of any kind.
At Derma Radiance & Wellness in Annandale, Virginia, PRF treatments are performed by Serki Tesfaye, FNP-BC — a board-certified Family Nurse Practitioner with a clinical background spanning intensive care, interventional radiology, and aesthetic medicine. Serki founded Derma Radiance & Wellness to offer inclusive, expert-level care for clients of all skin tones across Northern Virginia, Washington DC, and Maryland.
What Is PRF Therapy?
PRF — Platelet-Rich Fibrin — is a regenerative treatment made entirely from your own blood. Unlike traditional PRP (Platelet-Rich Plasma), PRF is processed without any anticoagulants or chemical additives, producing a thicker, more concentrated biological concentrate that works with your body's own repair systems in a uniquely powerful way.
Here is how PRF is prepared:
Step 1 — Blood Draw
A small amount of your blood is drawn in our office — the same as a routine lab draw.
Step 2 — Centrifuge Processing
Your blood is gently spun in a centrifuge — without any chemicals or anticoagulants — to concentrate platelets, fibrin, white blood cells, and growth factors into a biologically rich serum.
Step 3 — Fibrin Matrix Formation
The absence of anticoagulants allows the PRF to form a natural fibrin matrix — a scaffold that holds growth factors in place and releases them gradually over days to weeks, rather than all at once.
Step 4 — Application or Injection
The PRF concentrate is applied topically during microneedling or injected precisely into the treatment area — skin, under-eye region, or scalp — where it begins activating your body's regenerative processes immediately.
Step 5 — Gradual, Natural Results
Over the following weeks, collagen production increases, skin quality improves, and tissue is gently restored — delivering results that look and feel entirely natural because they are built entirely from within.
What Can PRF Treat?
Under-Eye Rejuvenation
PRF is one of the most effective natural treatments available for the delicate under-eye area. The slow-release growth factors gently address hollowing, fine lines, dark circles, and crepey texture in a zone where traditional fillers or topical products often fall short. Because PRF uses your own biology, results look naturally refreshed — not filled or overdone.
Facial Skin Rejuvenation
PRF stimulates collagen and elastin production throughout the face and neck, improving skin texture, tone, firmness, and overall radiance. Patients describe a gradual, natural improvement in skin quality — often referred to as the liquid collagen effect. PRF is an excellent option for clients seeking healthier, more luminous skin without injectables or synthetic substances.
Hair Restoration
PRF injected into the scalp delivers concentrated growth factors directly to hair follicles — stimulating dormant follicles, improving follicle health, and supporting the growth of thicker, healthier hair. This is a natural, non-surgical option for patients experiencing thinning hair or early hair loss, with results that improve progressively over a treatment series.
Combined With Microneedling
When PRF is applied during a microneedling treatment, the micro-channels created in the skin allow growth factors to penetrate deeply into the dermis — amplifying results for texture, tone, pigmentation, scarring, and overall skin renewal. This combination is one of the most popular advanced protocols at Derma Radiance & Wellness.
Advanced Regenerative Protocols
PRF is frequently paired with i-PRF and EZ-Gel in advanced protocols for patients seeking comprehensive facial rejuvenation using entirely natural biologics — no fillers, no toxins, no synthetic substances of any kind.
Tissue Repair and Post-Procedure Healing
The growth factors in PRF support tissue repair and accelerated healing, making PRF an effective adjunct to post-procedure recovery and skin restoration protocols.
Why PRF — The Advantages of Choosing All-Natural Regenerative Therapy
100% Natural and From Your Own Body
PRF is derived entirely from your own blood — no synthetic fillers, no foreign substances, no additives. Your body recognizes it completely, which means the risk of allergic reaction or rejection is virtually eliminated.
Slow-Release Growth Factors for Longer-Lasting Results
The fibrin matrix formed during PRF processing holds growth factors in place and releases them gradually over days to weeks — extending the regenerative window and delivering more sustained results compared to standard PRP.
More Biologically Rich Than Traditional PRP
By processing without anticoagulants, PRF captures a broader spectrum of regenerative biologics — including fibrin and white blood cells — that are lost in standard PRP preparation. This makes PRF a more concentrated and biologically active treatment.
Results That Look Exactly Like You
Because PRF works with your body's own natural regeneration timeline, results improve gradually and authentically. There is no sudden change, no "done" appearance — just a gradual restoration of your skin's natural quality and vitality.
Versatile and Combinable
PRF can be used alone or combined with microneedling, fillers, neurotoxins, Sculptra®, and other treatments for a fully personalized rejuvenation plan tailored to your specific goals.
PRP / PRF Differences
PRP Therapy and PRF Therapy are both powerful regenerative treatments derived from your own blood. Here is how they compare:
PRP
- Uses anticoagulants in processing
- Thinner consistency
- Faster growth factor release
- More immediate inflammatory response
- Excellent for combining with microneedling and hair restoration
PRF
- No anticoagulants — 100% natural processing
- Thicker, more concentrated consistency
- Slow-release growth factors over days to weeks
- More regenerative, less inflammatory
- Longer-lasting results
- Ideal for under-eye rejuvenation, facial skin quality, and advanced protocols
During your consultation, Serki will recommend whether PRP, PRF, or a combination approach is best suited to your treatment goals and skin condition.
How to Prepare for Your PRF Treatment
Before Your Appointment:
- Stay well-hydrated for 24 to 48 hours before your session — good hydration improves blood draw quality and PRF concentrate
- Avoid blood-thinning medications such as aspirin or ibuprofen for at least one week prior, if medically appropriate (consult your physician)
- Avoid alcohol for 24 to 48 hours before treatment
- Eat a light meal before your appointment — do not come fasting
- Avoid caffeine on the day of your appointment
- Arrive with clean skin, free of heavy makeup if possible
After Your Treatment:
- Avoid touching, rubbing, or applying pressure to the treated area for 24 hours
- Avoid alcohol and caffeine for 24 to 48 hours after treatment — both can affect circulation and healing
- Avoid intense exercise, saunas, and prolonged sun or heat exposure for 24 to 48 hours
- Do not wash the treated area for at least 24 hours if receiving scalp injections for hair restoration
- Mild redness, swelling, or tenderness at treatment sites is normal and typically resolves within a few days
- Stay well-hydrated and maintain a nutrient-rich diet to support your body's regenerative process
- Limit fatty foods and processed foods in the days following treatment
Is PRF Right for You? — Ideal Candidates
PRF may be the right treatment if you:
✅ Want a 100% natural treatment using only your own biology
✅ Are concerned about under-eye hollowing, fine lines, or crepey under-eye skin
✅ Want to improve overall skin texture, tone, and radiance gradually and naturally
✅ Are experiencing thinning hair or early-stage hair loss
✅ Prefer results that develop gradually and look entirely authentic
✅ Want to avoid synthetic fillers or foreign substances entirely
✅ Are looking to complement other treatments like microneedling or fillers with natural regenerative therapy
✅ Are a healthy adult in generally good health
PRF may NOT be recommended if you:
❌ Have a blood disorder or are on anticoagulant therapy
❌ Have active skin infection, inflammation, or open sores in the treatment area
❌ Have a history of certain cancers or are currently undergoing cancer treatment
❌ Are pregnant or breastfeeding
❌ Have a platelet dysfunction disorder or severe anemia
❌ Are immunocompromised (discuss with your provider)
Not sure if PRF is right for you? Schedule a consultation with Serki Tesfaye, FNP-BC — she will evaluate your health history, skin concerns, and goals to determine whether PRF, PRP, or a combination approach is the best fit for you.
The PRF Treatment Experience at Derma Radiance & Wellness
What to Expect at Your Appointment
A PRF session at Derma Radiance & Wellness is comfortable, efficient, and entirely in-office — with no general anesthesia, no surgery, and no significant downtime.
Most sessions follow this flow:
- Arrival and skin assessment (15 minutes)
- Blood draw — a small sample, same as a routine lab draw (5 minutes)
- Centrifuge processing of your PRF (10–15 minutes)
- Treatment — injection, topical application during microneedling, or both (20–40 minutes depending on areas treated)
- Aftercare instructions and follow-up plan
Total appointment time is typically 60 to 90 minutes.
How Many Sessions Will I Need?
For most PRF indications, a series of sessions delivers the best results. Serki will design your personalized treatment plan during your consultation, but general guidelines are:
- Skin rejuvenation: 3 to 4 sessions spaced 4 to 6 weeks apart
- Under-eye rejuvenation: 2 to 3 sessions spaced 4 to 6 weeks apart
- Hair restoration: 4 to 6 sessions spaced 4 to 6 weeks apart, followed by maintenance
5-Star Reviews for PRP & PRF Therapy in Northern Virginia
"I had the most gentle, classy, and truly blessed PRP microneedling experience with my beautiful friend Serki. From the moment I walked in, I felt completely cared for, pampered, and at peace. She truly has healing hands and a graceful spirit. My skin is already glowing, and I’m beyond grateful! May God continue to bless her hands and her work; she’s a light, and I’m so proud of her. Highly recommended!"
-Arsema
PRF Frequently Asked Questions
What is PRF and how is it different from PRP?
PRF (Platelet-Rich Fibrin) is the next generation of regenerative injectable therapy. Like PRP, it is made entirely from your own blood — but PRF is processed without anticoagulants, producing a thicker, more biologically rich concentrate that includes fibrin and white blood cells alongside platelets and growth factors. The fibrin matrix releases growth factors slowly over days to weeks, delivering longer-lasting regenerative results than standard PRP.
Is PRF better than PRP?
PRF is generally considered more advanced than traditional PRP because it contains a broader spectrum of regenerative biologics, releases growth factors more gradually for sustained results, and is processed without any chemical additives. That said, both are effective and the right choice depends on your specific treatment goals. Serki Tesfaye, FNP-BC will recommend the best option during your consultation.
How many PRF sessions do I need?
The number of sessions depends on your treatment area and goals. Most skin rejuvenation protocols involve 3 to 4 sessions spaced 4 to 6 weeks apart. Hair restoration typically requires 4 to 6 sessions. Under-eye rejuvenation may be addressed in 2 to 3 sessions. Serki will design your personalized plan during your consultation.
Is PRF safe for all skin tones?
Yes. PRF uses only your own blood — there are no foreign substances involved — making it safe and well-tolerated across all skin tones and types. At Derma Radiance & Wellness, inclusive care for clients of all backgrounds and complexions is a core commitment.
Is PRF painful?
PRF is well-tolerated by most patients. A topical numbing cream is applied before treatment to minimize discomfort. Most clients describe a mild pressure or pinching sensation during injections, which resolves quickly.
When will I see results from PRF?
Because PRF works with your body's natural regenerative timeline, results develop gradually. Most patients notice initial improvements in skin quality within 4 to 6 weeks of their first session, with continued improvement over the following months as collagen production increases.
How much does PRF cost in Northern Virginia?
At Derma Radiance & Wellness in Annandale, VA, PRF and PRP treatments start at $600 per session. Package pricing is available — 3 sessions at $1,620, 4 sessions at $1,920, and 6 sessions at $2,520. Members receive exclusive pricing. Visit Specials for current offers.
Where can I get PRF treatment near Washington DC?
Derma Radiance & Wellness offers PRF therapy at 7501 Little River Turnpike, Suite 203, Annandale, VA 22003. We serve clients from across Northern Virginia including Arlington, Alexandria, and Fairfax, as well as Washington DC and Maryland. Call (571) 899-3772 or book online.
Why should I avoid caffeine after PRF?
Caffeine can affect circulation and may interfere with your body's optimal healing response following PRF. Limiting caffeine intake for 24 to 48 hours after treatment supports the regenerative process and helps maximize your results.
What foods should I avoid after PRF?
In the 24 to 48 hours following your PRF treatment, it is best to limit alcohol, caffeine, and highly processed or fatty foods. These can affect circulation and inflammation levels, potentially interfering with your body's natural healing and regenerative response.
Book Your PRF Consultation in Annandale, VA
If you are ready to experience one of the most advanced natural regenerative treatments available — using only your own body's biology — PRF at Derma Radiance & Wellness is the next step.
Serki Tesfaye, FNP-BC and our team will guide you through every step of your PRF journey, from your initial consultation to your final results and ongoing care.
7501 Little River Turnpike, Suite 203, Annandale, VA 22003
We proudly serve clients from Annandale, Arlington, Alexandria, Fairfax, Northern Virginia, Washington DC, and Maryland.